Tumorigenesis promotes Mdm4-S overexpression

Disruption of the p53 tumor suppressor pathway is a primary cause of tumorigenesis. In addition to mutation of the p53 gene itself, overexpression of major negative regulators of p53, MDM2 and MDM4, also act as drivers for tumor development. Recent studies suggest that expression of splice variants...

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Detalles Bibliográficos
Autores principales: Pant, Vinod, Larsson, Connie A., Aryal, Neeraj, Xiong, Shunbin, You, M. James, Quintas-Cardama, Alfonso, Lozano, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432220/
https://www.ncbi.nlm.nih.gov/pubmed/28460439
http://dx.doi.org/10.18632/oncotarget.15552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432220/
https://www.ncbi.nlm.nih.gov/pubmed/28460439
http://dx.doi.org/10.18632/oncotarget.15552

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