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Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes

There is growing evidence that gene amplifications are an attribute of normal cells during development and differentiation. During neural progenitor cell differentiation half of the genome is involved in amplification process. To answer the question how specific amplifications occur at different sta...

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Detalles Bibliográficos
Autores principales: Fischer, Ulrike, Kim, Ella, Keller, Andreas, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432223/
https://www.ncbi.nlm.nih.gov/pubmed/28415661
http://dx.doi.org/10.18632/oncotarget.15980