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HIF-1α activates hypoxia-induced BCL-9 expression in human colorectal cancer cells

B-cell CLL/lymphoma 9 protein (BCL-9), a multi-functional co-factor in Wnt signaling, induced carcinogenesis as well as promoting tumor progression, metastasis and chemo-resistance in colorectal cancer (CRC). However, the mechanisms for increased BCL-9 expression in CRC were not well understood. Her...

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Detalles Bibliográficos
Autores principales: Tan, Zhen, Huang, Quan, Zang, Jia, Teng, Shi-Feng, Chen, Tian-Rui, Wei, Hai-feng, Song, Dian-Wen, Liu, Tie-Long, Yang, Xing-Hai, Fu, Chuan-Gang, Hu, Zhi-qian, Zhou, Wang, Yan, Wang-Jun, Xiao, Jian-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432224/
https://www.ncbi.nlm.nih.gov/pubmed/27121066
http://dx.doi.org/10.18632/oncotarget.8834