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CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy

Glioblastoma multiforme (GBM) is a rapidly progressive brain tumor with a median survival of 15–19 months. Therapeutic resistance and recurrence of the disease is attributed to cancer stem cells (CSC). Here, we report that CMV70-3P miRNA encoded by CMV increases GBM CSC stemness. Inhibition of CMV70...

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Detalles Bibliográficos
Autores principales: Ulasov, Ilya V., Kaverina, Natalya V., Ghosh, Dhimankrishna, Baryshnikova, Marya A., Kadagidze, Zaira G., Karseladze, Apollon I., Baryshnikov, Anatoly Y., Cobbs, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432232/
https://www.ncbi.nlm.nih.gov/pubmed/27517625
http://dx.doi.org/10.18632/oncotarget.11175