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Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

Lysyl Oxidase-like 2 (LOXL2), a member of the lysyl oxidase family of amine oxidases is known to be important in normal tissue development and homeostasis, as well as the onset and progression of solid tumors. Here we tested the anti-tumor properties of two generations of novel small molecule LOXL2...

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Detalles Bibliográficos
Autores principales: Chang, Joan, Lucas, Morghan C., Leonte, Lidia E., Garcia-Montolio, Marc, Singh, Lukram Babloo, Findlay, Alison D., Deodhar, Mandar, Foot, Jonathan S., Jarolimek, Wolfgang, Timpson, Paul, Erler, Janine T., Cox, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432238/
https://www.ncbi.nlm.nih.gov/pubmed/28199967
http://dx.doi.org/10.18632/oncotarget.15257