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Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma

Peripheral T-cell lymphomas (PTCLs) are aggressive non-Hodgkin lymphomas with generally poor outcomes following standard therapy. Few candidate therapeutic targets have been identified to date. Retinoic acid receptor alpha (RARA) is a transcription factor that modulates cell growth and differentiati...

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Detalles Bibliográficos
Autores principales: Wang, Xueju, Dasari, Surendra, Nowakowski, Grzegorz S., Lazaridis, Konstantinos N., Wieben, Eric D., Kadin, Marshall E., Feldman, Andrew L., Boddicker, Rebecca L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432253/
https://www.ncbi.nlm.nih.gov/pubmed/28412739
http://dx.doi.org/10.18632/oncotarget.15441