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microRNA-302c-3p inhibits renal cell carcinoma cell proliferation by targeting Grb2-associated binding 2 (Gab2)

The expression and biological function of Grb2-associated binding 2 (Gab2) in renal cell carcinoma (RCC) cells was tested here. We showed that Gab2 expression was significantly elevated in human RCC tissues and RCC cells. It was correlated with over-activation of Akt and downregulation of microRNA-3...

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Detalles Bibliográficos
Autores principales: Gu, Dong-Hua, Mao, Jia-Hui, Pan, Xiao-Dong, Zhu, Hua, Chen, Xinfeng, Zheng, Bing, Shan, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432261/
https://www.ncbi.nlm.nih.gov/pubmed/28412750
http://dx.doi.org/10.18632/oncotarget.15463