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Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer

CDC42 is an oncogenic Rho GTPase overexpressed in colorectal cancer (CRC). Although CDC42 has been shown to regulate gene transcription, the specific molecular mechanisms regulating the oncogenic ability of CDC42 remain unknown. Here, we have characterized the transcriptional networks governed by CD...

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Detalles Bibliográficos
Autores principales: Valdés-Mora, Fatima, Locke, Warwick J., Bandrés, Eva, Gallego-Ortega, David, Cejas, Paloma, García-Cabezas, Miguel Angel, Colino-Sanguino, Yolanda, Feliú, Jaime, del Pulgar, Teresa Gómez, Lacal, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432295/
https://www.ncbi.nlm.nih.gov/pubmed/28460460
http://dx.doi.org/10.18632/oncotarget.15815