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Tumor regression is mediated via the induction of HER2(63-71)- specific CD8+ CTL activity in a 4T1.2/HER2 tumor model: no involvement of CD80 in tumor control

In the CT26/HER2 and 4T1.2/HER2 tumor models, CT26/HER2 cells form tumors that continue to grow, whereas 4T1.2/HER2 cells form tumors that eventually regress. Here, we investigated the differences in the behaviors of these two cell lines. When immune cells from 4T1.2/HER2 tumor-bearing animals were...

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Detalles Bibliográficos
Autores principales: Danishmalik, Sayyed Nilofar, Lee, Si-Hyeong, Sin, Jeong-Im
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432296/
https://www.ncbi.nlm.nih.gov/pubmed/28460461
http://dx.doi.org/10.18632/oncotarget.15816