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SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation

Epigenetic modifications are essential in the control of normal cellular processes and cancer development. DNA methylation and histone acetylation are major epigenetic modifications involved in gene transcription and abnormal events driving the oncogenic process. SET protein accumulates in many canc...

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Detalles Bibliográficos
Autores principales: Almeida, Luciana O., Neto, Marinaldo P.C., Sousa, Lucas O., Tannous, Maryna A., Curti, Carlos, Leopoldino, Andreia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432298/
https://www.ncbi.nlm.nih.gov/pubmed/28460463
http://dx.doi.org/10.18632/oncotarget.15818