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SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation
Epigenetic modifications are essential in the control of normal cellular processes and cancer development. DNA methylation and histone acetylation are major epigenetic modifications involved in gene transcription and abnormal events driving the oncogenic process. SET protein accumulates in many canc...
Autores principales: | Almeida, Luciana O., Neto, Marinaldo P.C., Sousa, Lucas O., Tannous, Maryna A., Curti, Carlos, Leopoldino, Andreia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432298/ https://www.ncbi.nlm.nih.gov/pubmed/28460463 http://dx.doi.org/10.18632/oncotarget.15818 |
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