Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling

Higher levels of hyaluronan (HA) and its receptors CD44 and RHAMM have been associated with poor prognosis and metastasis in NSCLC. In the current study, our goal was to define, using cellular and orthotopic lung tumor models, the role of HA-CD44/RHAMM signaling in lung carcinogenesis and to assess...

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Detalles Bibliográficos
Autores principales: Song, Jung Min, Molla, Kalkidan, Anandharaj, Arunkumar, Cornax, Ingrid, O`Sullivan, M. Gerard, Kirtane, Ameya R., Panyam, Jayanth, Kassie, Fekadu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432308/
https://www.ncbi.nlm.nih.gov/pubmed/28460475
http://dx.doi.org/10.18632/oncotarget.15879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432308/
https://www.ncbi.nlm.nih.gov/pubmed/28460475
http://dx.doi.org/10.18632/oncotarget.15879

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