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The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth

The extracellular matrix plays a fundamental role in physiological and pathological proliferation. It exerts its function through a signal cascade starting from the integrins that take direct contact with matrix constituents most of which behave as pro-proliferative clues. On the contrary, EMILIN1,...

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Detalles Bibliográficos
Autores principales: Modica, Teresa Maria Elisa, Maiorani, Orlando, Sartori, Giulio, Pivetta, Eliana, Doliana, Roberto, Capuano, Alessandra, Colombatti, Alfonso, Spessotto, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432316/
https://www.ncbi.nlm.nih.gov/pubmed/28177903
http://dx.doi.org/10.18632/oncotarget.15067