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The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth
The extracellular matrix plays a fundamental role in physiological and pathological proliferation. It exerts its function through a signal cascade starting from the integrins that take direct contact with matrix constituents most of which behave as pro-proliferative clues. On the contrary, EMILIN1,...
Autores principales: | Modica, Teresa Maria Elisa, Maiorani, Orlando, Sartori, Giulio, Pivetta, Eliana, Doliana, Roberto, Capuano, Alessandra, Colombatti, Alfonso, Spessotto, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432316/ https://www.ncbi.nlm.nih.gov/pubmed/28177903 http://dx.doi.org/10.18632/oncotarget.15067 |
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