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Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice

Lysophosphatidic acid (LPA), a bioactive lysophospholipid, is involved in the pathogenesis of chronic inflammatory and autoimmune diseases. In this study, we investigated the role of LPA/LPA receptor (LPAR) signaling in the pathogenesis of Sjögren's syndrome (SS). We found that autotaxin, an LP...

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Detalles Bibliográficos
Autores principales: Park, Eunhye, Kim, Donghee, Lee, Song Mi, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432331/
https://www.ncbi.nlm.nih.gov/pubmed/28460477
http://dx.doi.org/10.18632/oncotarget.15916