SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development

The non-receptor tyrosine phosphatase SHP2 has scaffolding functions in signal transduction cascades downstream of growth receptors. A recent study suggested that SHP2 acts as a tumor suppressor during hepatocellular carcinoma (HCC) development. Herein we examined whether SHP2 links the HBx–NF-κB pa...

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Detalles Bibliográficos
Autores principales: Kang, Hyo Jeong, Chung, Dal-Hee, Sung, Chang Ohk, Yoo, Su Hyun, Yu, Eunsil, Kim, Nayoung, Lee, Sy-Hye, Song, Ji-Young, Kim, Chong Jai, Choi, Jene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432333/
https://www.ncbi.nlm.nih.gov/pubmed/28460481
http://dx.doi.org/10.18632/oncotarget.15930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432333/
https://www.ncbi.nlm.nih.gov/pubmed/28460481
http://dx.doi.org/10.18632/oncotarget.15930

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