Improvement of dexamethasone sensitivity by chelation of intracellular Ca(2+) in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation

Previous studies have demonstrated that glucocorticoid hormones, including dexamethasone, induced alterations in intracellular calcium homeostasis in acute lymphoblastic leukemia (ALL) cells. However, the mechanism by which intracellular calcium homeostasis participates in dexamethasone sensitivity...

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Detalles Bibliográficos
Autores principales: Abdoul-Azize, Souleymane, Dubus, Isabelle, Vannier, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432339/
https://www.ncbi.nlm.nih.gov/pubmed/28423696
http://dx.doi.org/10.18632/oncotarget.16039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432339/
https://www.ncbi.nlm.nih.gov/pubmed/28423696
http://dx.doi.org/10.18632/oncotarget.16039

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