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Improvement of dexamethasone sensitivity by chelation of intracellular Ca(2+) in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation
Previous studies have demonstrated that glucocorticoid hormones, including dexamethasone, induced alterations in intracellular calcium homeostasis in acute lymphoblastic leukemia (ALL) cells. However, the mechanism by which intracellular calcium homeostasis participates in dexamethasone sensitivity...
Autores principales: | Abdoul-Azize, Souleymane, Dubus, Isabelle, Vannier, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432339/ https://www.ncbi.nlm.nih.gov/pubmed/28423696 http://dx.doi.org/10.18632/oncotarget.16039 |
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