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A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity

The intracellular pathogen Mycobacterium tuberculosis (Mtb) lives within phagosomes and also disrupts these organelles to access the cytosol. The host pathways and mechanisms that contribute to maintaining Mtb phagosome integrity have not been investigated. Here, we examined the spatiotemporal dynam...

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Detalles Bibliográficos
Autores principales: Schnettger, Laura, Rodgers, Angela, Repnik, Urska, Lai, Rachel P., Pei, Gang, Verdoes, Martijn, Wilkinson, Robert J., Young, Douglas B., Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432432/
https://www.ncbi.nlm.nih.gov/pubmed/28494243
http://dx.doi.org/10.1016/j.chom.2017.04.004