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A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity
The intracellular pathogen Mycobacterium tuberculosis (Mtb) lives within phagosomes and also disrupts these organelles to access the cytosol. The host pathways and mechanisms that contribute to maintaining Mtb phagosome integrity have not been investigated. Here, we examined the spatiotemporal dynam...
Autores principales: | Schnettger, Laura, Rodgers, Angela, Repnik, Urska, Lai, Rachel P., Pei, Gang, Verdoes, Martijn, Wilkinson, Robert J., Young, Douglas B., Gutierrez, Maximiliano G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432432/ https://www.ncbi.nlm.nih.gov/pubmed/28494243 http://dx.doi.org/10.1016/j.chom.2017.04.004 |
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