Improving the temperature characteristics and catalytic efficiency of a mesophilic xylanase from Aspergillus oryzae, AoXyn11A, by iterative mutagenesis based on in silico design

To improve the temperature characteristics and catalytic efficiency of a glycoside hydrolase family (GHF) 11 xylanase from Aspergillus oryzae (AoXyn11A), its variants were predicted based on in silico design. Firstly, Gly(21) with the maximum B-factor value, which was confirmed by molecular dynamics...

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Detalles Bibliográficos
Autores principales: Li, Xue-Qing, Wu, Qin, Hu, Die, Wang, Rui, Liu, Yan, Wu, Min-Chen, Li, Jian-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432455/
https://www.ncbi.nlm.nih.gov/pubmed/28508385
http://dx.doi.org/10.1186/s13568-017-0399-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432455/
https://www.ncbi.nlm.nih.gov/pubmed/28508385
http://dx.doi.org/10.1186/s13568-017-0399-9

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