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Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice

The purinergic P2X7 receptor (P2X7R) has attracted considerable interest as a potential target for various central nervous system (CNS) pathologies including affective and neurodegenerative disorders. To date, the distribution and cellular localization of the P2X7R in the brain are not fully resolve...

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Detalles Bibliográficos
Autores principales: Metzger, Michael W., Walser, Sandra M., Aprile-Garcia, Fernando, Dedic, Nina, Chen, Alon, Holsboer, Florian, Arzt, Eduardo, Wurst, Wolfgang, Deussing, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432476/
https://www.ncbi.nlm.nih.gov/pubmed/27858314
http://dx.doi.org/10.1007/s11302-016-9546-z