BNIP3L promotes cardiac fibrosis in cardiac fibroblasts through [Ca(2+)](i)-TGF-β-Smad2/3 pathway

Fibrosis is an important, structurally damaging event that occurs in pathological cardiac remodeling, leading to cardiac dysfunction. BNIP3L is up-regulated in pressure overload-induced heart failure and has been reported to play an important role in cardiomyocyte apoptosis; however, its involvement...

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Detalles Bibliográficos
Autores principales: Liu, Weili, Wang, Xinxing, Mei, Zhusong, Gong, Jingbo, Huang, lishuang, Gao, Xiujie, Zhao, Yun, Ma, Jing, Qian, Lingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432493/
https://www.ncbi.nlm.nih.gov/pubmed/28507335
http://dx.doi.org/10.1038/s41598-017-01936-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432493/
https://www.ncbi.nlm.nih.gov/pubmed/28507335
http://dx.doi.org/10.1038/s41598-017-01936-5

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