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BNIP3L promotes cardiac fibrosis in cardiac fibroblasts through [Ca(2+)](i)-TGF-β-Smad2/3 pathway
Fibrosis is an important, structurally damaging event that occurs in pathological cardiac remodeling, leading to cardiac dysfunction. BNIP3L is up-regulated in pressure overload-induced heart failure and has been reported to play an important role in cardiomyocyte apoptosis; however, its involvement...
Autores principales: | Liu, Weili, Wang, Xinxing, Mei, Zhusong, Gong, Jingbo, Huang, lishuang, Gao, Xiujie, Zhao, Yun, Ma, Jing, Qian, Lingjia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432493/ https://www.ncbi.nlm.nih.gov/pubmed/28507335 http://dx.doi.org/10.1038/s41598-017-01936-5 |
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