Cargando…

A One-Pot Three-Component Double-Click Method for Synthesis of [(67)Cu]-Labeled Biomolecular Radiotherapeutics

A one-pot three-component double-click process for preparing tumor-targeting agents for cancer radiotherapy is described here. By utilizing DOTA (or NOTA) containing tetrazines and the TCO-substituted aldehyde, the two click reactions, the tetrazine ligation (an inverse electron-demand Diels-Alder c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujiki, Katsumasa, Yano, Shinya, Ito, Takeshi, Kumagai, Yuki, Murakami, Yoshinori, Kamigaito, Osamu, Haba, Hiromitsu, Tanaka, Katsunori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432496/ https://www.ncbi.nlm.nih.gov/pubmed/28507297 http://dx.doi.org/10.1038/s41598-017-02123-2

Ejemplares similares

(211)At-labeled immunoconjugate via a one-pot three-component double click strategy: practical access to α-emission cancer radiotherapeutics
por: Fujiki, Katsumasa, et al.
Publicado: (2018)

One-Pot Synthesis of Polypyrazoles by Click Reactions
por: Wang, Shasha, et al.
Publicado: (2017)

Oxidation-Induced “One-Pot” Click Chemistry
por: Albada, Bauke, et al.
Publicado: (2021)

CLICK—topology-independent comparison of biomolecular 3D structures
por: Nguyen, M. N., et al.
Publicado: (2011)

Integrin Targeted Delivery of Radiotherapeutics
por: Liu, Zhaofei, et al.
Publicado: (2011)

Regulatory T Cells in Radiotherapeutic Responses
por: Schaue, Dörthe, et al.
Publicado: (2012)

Native structure-based modeling and simulation of biomolecular systems per mouse click
por: Lutz, Benjamin, et al.
Publicado: (2014)

One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions
por: Ma, Xiaoming, et al.
Publicado: (2019)

A synthetic approach to ‘click’ neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry
por: Lee, D. J., et al.
Publicado: (2018)

A new synthetic pathway based on one-pot sequential aza-Michael addition and photoCuAAC click reactions
por: Yin, Boyang, et al.
Publicado: (2019)

Radiotherapeutic alternatives for previously irradiated recurrent gliomas
por: Combs, Stephanie E, et al.
Publicado: (2007)

Immunogenic Effect of Hyperthermia on Enhancing Radiotherapeutic Efficacy
por: Lee, Sungmin, et al.
Publicado: (2018)

STAT3, the Challenge for Chemotherapeutic and Radiotherapeutic Efficacy
por: Yang, Ping-Lian, et al.
Publicado: (2020)

Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
por: Latypova, Liliya, et al.
Publicado: (2016)

Radiotherapeutic Strategies in the Management of Low-Risk Prostate Cancer
por: Choe, Kevin S., et al.
Publicado: (2010)

Radiotherapeutic treatment options for oligotopic malignant liver lesions
por: Wust, Peter, et al.
Publicado: (2021)

Synthesis of Isotactic-block-Syndiotactic Poly(methyl Methacrylate) via Stereospecific Living Anionic Polymerizations in Combination with Metal-Halogen Exchange, Halogenation, and Click Reactions
por: Usuki, Naoya, et al.
Publicado: (2017)

Magnetic moment of $^{67}$Ni and $^{67}$Ni $\rightarrow ^{67}$Cu $\beta$-decay
por: Ríkovská, J, et al.
Publicado: (1996)

Yttrium-90-EDTMP: a radiotherapeutic agent in the treatment of leukaemias.
por: Keeling, A. A., et al.
Publicado: (1989)

Clinical practice guideline on the optimal radiotherapeutic management of brain metastases
por: Tsao, May N, et al.
Publicado: (2005)

Local radiotherapeutic management of ependymomas with fractionated stereotactic radiotherapy (FSRT)
por: Combs, Stephanie E, et al.
Publicado: (2006)

Müllerian duct anomalies and their effect on the radiotherapeutic management of cervical cancer
por: Rastogi, Madhup, et al.
Publicado: (2013)

Tailored radiotherapeutic strategies for disseminated uterine cervical cancer patients
por: Im, Jung Ho, et al.
Publicado: (2015)

Pulmonary toxicity generated from radiotherapeutic treatment of thoracic malignancies
por: Deng, Guodong, et al.
Publicado: (2017)

Design of Internalizing PSMA-specific Glu-ureido-based Radiotherapeuticals
por: Wüstemann, Till, et al.
Publicado: (2016)

Radiotherapeutic management of brain tumours during the COVID-19 pandemic
por: Balakrishnan, Rajesh, et al.
Publicado: (2020)

Is (70)Zn(d,x)(67)Cu the Best Way to Produce (67)Cu for Medical Applications?
por: Nigron, Etienne, et al.
Publicado: (2021)

Pattern Recognition: Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo (Adv. Sci. 2/2017)
por: Latypova, Liliya, et al.
Publicado: (2017)

A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry
por: Sletten, Ellen M., et al.
Publicado: (2008)

Peptide Conjugation via CuAAC ‘Click’ Chemistry
por: Ahmad Fuaad, Abdullah A. H., et al.
Publicado: (2013)

High-affinity multivalent wheat germ agglutinin ligands by one-pot click reaction
por: Beckmann, Henning S G, et al.
Publicado: (2012)

Recent Advances in (64)Cu/(67)Cu-Based Radiopharmaceuticals
por: Krasnovskaya, Olga O., et al.
Publicado: (2023)

CLICK-17, a DNA enzyme that harnesses ultra-low concentrations of either Cu(+) or Cu(2+) to catalyze the azide-alkyne ‘click’ reaction in water
por: Liu, Kun, et al.
Publicado: (2020)

Machine Learning-Based Radiomics Predicts Radiotherapeutic Response in Patients With Acromegaly
por: Fan, Yanghua, et al.
Publicado: (2019)

Survival Disparities in the Radiotherapeutic Management of Lung Cancer by Regional Poverty Level
por: Mahase, Sean, et al.
Publicado: (2018)

Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect
por: Jing, Di, et al.
Publicado: (2022)

Rapid Cu-Free Click Chemistry with Readily Synthesized Biarylazacyclooctynones
por: Jewett, John C., et al.
Publicado: (2010)

Designing Click One-Pot Synthesis and Antidiabetic Studies of 1,2,3-Triazole Derivatives
por: Shafique, Kainat, et al.
Publicado: (2023)

Cyclotron-Based Production of (67)Cu for Radionuclide Theranostics via the (70)Zn(p,α)(67)Cu Reaction
por: Brühlmann, Santiago Andrés, et al.
Publicado: (2023)

Click, Click
por: Adashek, Jacob
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jum16a2q3iaeua15ci1bnaajv9