A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β(1) pathways

Renal fibrosis is closely related to chronic inflammation and is under the control of epigenetic regulations. Because the signaling of transforming growth factor-β(1) (TGF-β(1)) and tumor necrosis factor-α (TNF-α) play key roles in progression of renal fibrosis, dual blockade of TGF-β(1) and TNF-α i...

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Detalles Bibliográficos
Autores principales: Shima, Hisato, Sasaki, Kensuke, Suzuki, Takehiro, Mukawa, Chikahisa, Obara, Ten, Oba, Yuki, Matsuo, Akihiro, Kobayashi, Takayasu, Mishima, Eikan, Watanabe, Shun, Akiyama, Yasutoshi, Kikuchi, Koichi, Matsuhashi, Tetsuro, Oikawa, Yoshitsugu, Nanto, Fumika, Akiyama, Yukako, Ho, Hsin-Jung, Suzuki, Chitose, Saigusa, Daisuke, Masamune, Atsushi, Tomioka, Yoshihisa, Masaki, Takao, Ito, Sadayoshi, Hayashi, Ken-ichiro, Abe, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432497/
https://www.ncbi.nlm.nih.gov/pubmed/28507324
http://dx.doi.org/10.1038/s41598-017-01702-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432497/
https://www.ncbi.nlm.nih.gov/pubmed/28507324
http://dx.doi.org/10.1038/s41598-017-01702-7

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