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The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study

Leucine (Leu) is a multifunctional essential amino acid that plays crucial role in various cellular processes. However, the integral effect of Leu on the hepatic proteome remains largely unknown. Here, we for the first time applied an isobaric tags for relative and absolute quantification (iTRAQ)-ba...

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Detalles Bibliográficos
Autores principales: Yan, Guokai, Li, Xiuzhi, Peng, Ying, Long, Baisheng, Fan, Qiwen, Wang, Zhichang, Shi, Min, Xie, Chunlin, Zhao, Li, Yan, Xianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432498/
https://www.ncbi.nlm.nih.gov/pubmed/28507299
http://dx.doi.org/10.1038/s41598-017-02131-2