Disruption of SHH signaling cascade by SBE attenuates lung cancer progression and sensitizes DDP treatment

Deregulated Sonic Hedgehog (SHH) pathway facilitates the initiation, progression, and metastasis of Non-small cell lung cancer (NSCLC), confers drug resistance and renders a therapeutic interference option to lung cancer patients with poor prognosis. In this study, we screened and evaluated the spec...

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Detalles Bibliográficos
Autores principales: Du, Jing, Chen, Weiwei, Yang, Lijuan, Dai, Juanjuan, Guo, Jiwei, Wu, Yan, Gong, Kaikai, Zhang, Jian, Yu, Ning, Xie, Zhen, Xi, Sichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432500/
https://www.ncbi.nlm.nih.gov/pubmed/28507311
http://dx.doi.org/10.1038/s41598-017-02063-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432500/
https://www.ncbi.nlm.nih.gov/pubmed/28507311
http://dx.doi.org/10.1038/s41598-017-02063-x

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