Pro-inflammatory Ca(++)-activated K(+) channels are inhibited by hydroxychloroquine

Antimalarials have demonstrated beneficial effects in Systemic Lupus Erithematosus and Rheumatoid Arthritis. However, the mechanisms and the molecular players targeted by these drugs remain obscure. Although hydroxychloroquine (HCQ) is a known ion channel inhibitor, this property has not been linked...

Descripción completa

Detalles Bibliográficos
Autores principales: Eugenia Schroeder, María, Russo, Sofía, Costa, Carlos, Hori, Juliana, Tiscornia, Inés, Bollati-Fogolín, Mariela, Zamboni, Darío S, Ferreira, Gonzalo, Cairoli, Ernesto, Hill, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432501/
https://www.ncbi.nlm.nih.gov/pubmed/28507328
http://dx.doi.org/10.1038/s41598-017-01836-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432501/
https://www.ncbi.nlm.nih.gov/pubmed/28507328
http://dx.doi.org/10.1038/s41598-017-01836-8

Ejemplares similares