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Molecular and functional characterization of the BMPR2 gene in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension is a progressive disease that causes the obstruction of precapillary pulmonary arteries and a sustained increase in pulmonary vascular resistance. The aim was to analyze functionally the variants found in the BMPR2 gene and to establish a genotype-phenotype correlatio...

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Detalles Bibliográficos
Autores principales: Pousada, Guillermo, Lupo, Vincenzo, Cástro-Sánchez, Sheila, Álvarez-Satta, María, Sánchez-Monteagudo, Ana, Baloira, Adolfo, Espinós, Carmen, Valverde, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432510/
https://www.ncbi.nlm.nih.gov/pubmed/28507310
http://dx.doi.org/10.1038/s41598-017-02074-8