PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma

Recurrence following chemotherapy is observed in the majority of patients with pancreatic ductal adenocarcinoma (PDAC). Recent studies suggest that cancer stem cells (CSCs) may be involved in PDAC recurrence and metastasis. However, an efficient approach to targeting pancreatic CSCs remains to be es...

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Detalles Bibliográficos
Autores principales: Kumazoe, Motofumi, Takai, Mika, Hiroi, Shun, Takeuchi, Chieri, Yamanouchi, Maasa, Nojiri, Takashi, Onda, Hiroaki, Bae, Jaehoon, Huang, Yuhui, Takamatsu, Kanako, Yamashita, Shuya, Yamada, Shuhei, Kangawa, Kenji, Takahashi, Takashi, Tanaka, Hiroshi, Tachibana, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432527/
https://www.ncbi.nlm.nih.gov/pubmed/28507327
http://dx.doi.org/10.1038/s41598-017-02162-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432527/
https://www.ncbi.nlm.nih.gov/pubmed/28507327
http://dx.doi.org/10.1038/s41598-017-02162-9

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