Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae

Efficient production of sesquiterpenes in Saccharomyces cerevisiae requires a high flux through the mevalonate pathway. To achieve this, the supply of acetyl-CoA plays a crucial role, partially because nine moles of acetyl-CoA are necessary to produce one mole of farnesyl diphosphate, but also to ov...

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Detalles Bibliográficos
Autores principales: Tippmann, Stefan, Ferreira, Raphael, Siewers, Verena, Nielsen, Jens, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Metabolic Engineering & Synthetic Biology - Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432608/
https://www.ncbi.nlm.nih.gov/pubmed/28185100
http://dx.doi.org/10.1007/s10295-017-1911-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432608/
https://www.ncbi.nlm.nih.gov/pubmed/28185100
http://dx.doi.org/10.1007/s10295-017-1911-6

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