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Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae
Efficient production of sesquiterpenes in Saccharomyces cerevisiae requires a high flux through the mevalonate pathway. To achieve this, the supply of acetyl-CoA plays a crucial role, partially because nine moles of acetyl-CoA are necessary to produce one mole of farnesyl diphosphate, but also to ov...
Autores principales: | Tippmann, Stefan, Ferreira, Raphael, Siewers, Verena, Nielsen, Jens, Chen, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432608/ https://www.ncbi.nlm.nih.gov/pubmed/28185100 http://dx.doi.org/10.1007/s10295-017-1911-6 |
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