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Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase

Human ornithine δ-aminotransferase (hOAT) (EC 2.6.1.13) is a mitochondrial pyridoxal 5′-phosphate (PLP)-dependent aminotransferase whose deficit is associated with gyrate atrophy, a rare autosomal recessive disorder causing progressive blindness and chorioretinal degeneration. Here, both the apo- an...

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Detalles Bibliográficos
Autores principales: Montioli, Riccardo, Zamparelli, Carlotta, Borri Voltattorni, Carla, Cellini, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432616/
https://www.ncbi.nlm.nih.gov/pubmed/28345116
http://dx.doi.org/10.1007/s10930-017-9710-5