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Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase
Human ornithine δ-aminotransferase (hOAT) (EC 2.6.1.13) is a mitochondrial pyridoxal 5′-phosphate (PLP)-dependent aminotransferase whose deficit is associated with gyrate atrophy, a rare autosomal recessive disorder causing progressive blindness and chorioretinal degeneration. Here, both the apo- an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432616/ https://www.ncbi.nlm.nih.gov/pubmed/28345116 http://dx.doi.org/10.1007/s10930-017-9710-5 |