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Effects of siRNA-mediated HIF-1α gene silencing on angiogenesis in osteosarcoma
OBJECTIVE: To explore angiogenesis in osteosarcoma under the condition of hypoxia-inducible factor (HIF)-1α gene silenced by small interference RNA (siRNA). METHODS: The SaOS-2 osteosarcoma cells, transfected with the recombinant plasmid pSilencer2.1-HIF-1α or pSilencer2.1-SCR, were classified as HI...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Professional Medical Publications
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432701/ https://www.ncbi.nlm.nih.gov/pubmed/28523034 http://dx.doi.org/10.12669/pjms.332.12587 |