Vasorelaxing and antihypertensive activities of synthesized peptides derived from computer-aided simulation of pepsin hydrolysis of yam dioscorin

BACKGROUND: We reported that yam dioscorin and its peptic hydrolysates exhibited ACE inhibition and antihypertensive effects on SHRs, however, the active peptides are not really isolated until now. Using ACE inhibitory screenings, two penta-peptides, KTCGY and KRIHF, were selected for ex vivo and in...

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Detalles Bibliográficos
Autores principales: Lin, Yin-Shiou, Lu, Yeh-Lin, Wang, Guei-Jane, Liang, Hong-Jen, Hou, Wen-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432742/
https://www.ncbi.nlm.nih.gov/pubmed/28510941
http://dx.doi.org/10.1186/s40529-014-0049-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432742/
https://www.ncbi.nlm.nih.gov/pubmed/28510941
http://dx.doi.org/10.1186/s40529-014-0049-3

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