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KRAS G12C mutation as a poor prognostic marker of pemetrexed treatment in non-small cell lung cancer

BACKGROUND/AIMS: The predictive and prognostic value of KRAS mutation and its type of mutations in non-small cell lung cancer (NSCLC) are controversial. This clinical study was designed to investigate the predictive value of KRAS mutations and its mutation types to pemetrexed and gemcitabine based t...

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Detalles Bibliográficos
Autores principales: Park, Sehhoon, Kim, Ji-Yeon, Lee, Se-Hoon, Suh, Beomseok, Keam, Bhumsuk, Kim, Tae Min, Kim, Dong-Wan, Heo, Dae Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432792/
https://www.ncbi.nlm.nih.gov/pubmed/28407465
http://dx.doi.org/10.3904/kjim.2015.299