The seroprevalence of Bartonella henselae in healthy adults in Korea

BACKGROUND/AIMS: Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. However, only several cases of B. henselae infection have been reported in Korea. This study investigated the seroprevalence of B. henselae in healthy adults and related risk factors. METHOD...

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Autores principales: Kwon, Hea Yoon, Im, Jae Hyoung, Lee, Sun Myoung, Baek, Ji Hyeon, Durey, Areum, Park, Shin-Goo, Kang, Jae-Seung, Lee, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432800/
https://www.ncbi.nlm.nih.gov/pubmed/28490714
http://dx.doi.org/10.3904/kjim.2016.010
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author Kwon, Hea Yoon
Im, Jae Hyoung
Lee, Sun Myoung
Baek, Ji Hyeon
Durey, Areum
Park, Shin-Goo
Kang, Jae-Seung
Lee, Jin-Soo
author_facet Kwon, Hea Yoon
Im, Jae Hyoung
Lee, Sun Myoung
Baek, Ji Hyeon
Durey, Areum
Park, Shin-Goo
Kang, Jae-Seung
Lee, Jin-Soo
author_sort Kwon, Hea Yoon
collection PubMed
description BACKGROUND/AIMS: Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. However, only several cases of B. henselae infection have been reported in Korea. This study investigated the seroprevalence of B. henselae in healthy adults and related risk factors. METHODS: Serum samples from 300 healthy participants were analyzed using an immunoglobulin G immunof luorescence assay (IFA) for B. henselae isolated in Korea. Surveys on the risk factors for B. henselae infection were conducted simultaneously. RESULTS: Of the participants, 47.7% and 15.0% raised dogs and cats, respectively. The overall seroprevalence of B. henselae was 15.0% (IFA titer ≥ 1:64). Participants who had raised cats showed 22.2% seropositivity against B. henselae, and those with no experience with cats showed 13.7% seroprevalence (p = 0.17). Participants who had cats as pets or been scratched by cats, showed 9.8% seropositivity against B. henselae (IFA titer ≥ 1:256). However, those who had not raised or been scratched by a cat showed 2.0% seropositivity (p = 0.015). CONCLUSIONS: In Korea, the seroprevalence of B. henselae is higher than expected, suggesting that Bartonella infection due to B. henselae is not uncommon. Cats are proposed to play a more important role than dogs in transmission of CSD.
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spelling pubmed-54328002017-05-17 The seroprevalence of Bartonella henselae in healthy adults in Korea Kwon, Hea Yoon Im, Jae Hyoung Lee, Sun Myoung Baek, Ji Hyeon Durey, Areum Park, Shin-Goo Kang, Jae-Seung Lee, Jin-Soo Korean J Intern Med Original Article BACKGROUND/AIMS: Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. However, only several cases of B. henselae infection have been reported in Korea. This study investigated the seroprevalence of B. henselae in healthy adults and related risk factors. METHODS: Serum samples from 300 healthy participants were analyzed using an immunoglobulin G immunof luorescence assay (IFA) for B. henselae isolated in Korea. Surveys on the risk factors for B. henselae infection were conducted simultaneously. RESULTS: Of the participants, 47.7% and 15.0% raised dogs and cats, respectively. The overall seroprevalence of B. henselae was 15.0% (IFA titer ≥ 1:64). Participants who had raised cats showed 22.2% seropositivity against B. henselae, and those with no experience with cats showed 13.7% seroprevalence (p = 0.17). Participants who had cats as pets or been scratched by cats, showed 9.8% seropositivity against B. henselae (IFA titer ≥ 1:256). However, those who had not raised or been scratched by a cat showed 2.0% seropositivity (p = 0.015). CONCLUSIONS: In Korea, the seroprevalence of B. henselae is higher than expected, suggesting that Bartonella infection due to B. henselae is not uncommon. Cats are proposed to play a more important role than dogs in transmission of CSD. The Korean Association of Internal Medicine 2017-05 2017-04-20 /pmc/articles/PMC5432800/ /pubmed/28490714 http://dx.doi.org/10.3904/kjim.2016.010 Text en Copyright © 2017 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kwon, Hea Yoon
Im, Jae Hyoung
Lee, Sun Myoung
Baek, Ji Hyeon
Durey, Areum
Park, Shin-Goo
Kang, Jae-Seung
Lee, Jin-Soo
The seroprevalence of Bartonella henselae in healthy adults in Korea
title The seroprevalence of Bartonella henselae in healthy adults in Korea
title_full The seroprevalence of Bartonella henselae in healthy adults in Korea
title_fullStr The seroprevalence of Bartonella henselae in healthy adults in Korea
title_full_unstemmed The seroprevalence of Bartonella henselae in healthy adults in Korea
title_short The seroprevalence of Bartonella henselae in healthy adults in Korea
title_sort seroprevalence of bartonella henselae in healthy adults in korea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432800/
https://www.ncbi.nlm.nih.gov/pubmed/28490714
http://dx.doi.org/10.3904/kjim.2016.010
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