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Kaposi's Sarcoma-Associated Herpesvirus Hijacks RNA Polymerase II To Create a Viral Transcriptional Factory

Locally concentrated nuclear factors ensure efficient binding to DNA templates, facilitating RNA polymerase II recruitment and frequent reutilization of stable preinitiation complexes. We have uncovered a mechanism for effective viral transcription by focal assembly of RNA polymerase II around Kapos...

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Detalles Bibliográficos
Autores principales: Chen, Christopher Phillip, Lyu, Yuanzhi, Chuang, Frank, Nakano, Kazushi, Izumiya, Chie, Jin, Di, Campbell, Mel, Izumiya, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432858/
https://www.ncbi.nlm.nih.gov/pubmed/28331082
http://dx.doi.org/10.1128/JVI.02491-16