Cargando…

Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency

BACKGROUND: Even though hematopoietic stem cell transplantation can be curative in patients with severe combined immunodeficiency, there is a need for additional strategies boosting T cell immunity in individuals suffering from genetic disorders of lymphoid development. Here we show that image-guide...

Descripción completa

Detalles Bibliográficos
Autores principales: Tuckett, Andrea Z., Thornton, Raymond H., O’Reilly, Richard J., van den Brink, Marcel R. M., Zakrzewski, Johannes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432974/
https://www.ncbi.nlm.nih.gov/pubmed/28511686
http://dx.doi.org/10.1186/s13045-017-0478-z