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Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency
BACKGROUND: Even though hematopoietic stem cell transplantation can be curative in patients with severe combined immunodeficiency, there is a need for additional strategies boosting T cell immunity in individuals suffering from genetic disorders of lymphoid development. Here we show that image-guide...
Autores principales: | Tuckett, Andrea Z., Thornton, Raymond H., O’Reilly, Richard J., van den Brink, Marcel R. M., Zakrzewski, Johannes L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432974/ https://www.ncbi.nlm.nih.gov/pubmed/28511686 http://dx.doi.org/10.1186/s13045-017-0478-z |
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