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In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants

BACKGROUND: Genome-wide association studies have identified 55 genetic variants associated with colorectal cancer risk to date. However, potential causal genes and pathways regulated by these risk variants remain to be characterized. Therefore, we performed gene ontology enrichment and pathway analy...

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Detalles Bibliográficos
Autores principales: Loo, Lenora W. M., Lemire, Mathieu, Le Marchand, Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432975/
https://www.ncbi.nlm.nih.gov/pubmed/28506205
http://dx.doi.org/10.1186/s12864-017-3750-2