Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data

BACKGROUND: Understanding the mapping precision of genome-wide association studies (GWAS), that is the physical distances between the top associated single-nucleotide polymorphisms (SNPs) and the causal variants, is essential to design fine-mapping experiments for complex traits and diseases. RESULT...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yang, Zheng, Zhili, Visscher, Peter M., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979/
https://www.ncbi.nlm.nih.gov/pubmed/28506277
http://dx.doi.org/10.1186/s13059-017-1216-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979/
https://www.ncbi.nlm.nih.gov/pubmed/28506277
http://dx.doi.org/10.1186/s13059-017-1216-0

Ejemplares similares