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Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data
BACKGROUND: Understanding the mapping precision of genome-wide association studies (GWAS), that is the physical distances between the top associated single-nucleotide polymorphisms (SNPs) and the causal variants, is essential to design fine-mapping experiments for complex traits and diseases. RESULT...
Autores principales: | Wu, Yang, Zheng, Zhili, Visscher, Peter M., Yang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979/ https://www.ncbi.nlm.nih.gov/pubmed/28506277 http://dx.doi.org/10.1186/s13059-017-1216-0 |
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