Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB

Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB. Both toxins coordinate the action of specific domains to bind receptors, enter cells, an...

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Detalles Bibliográficos
Autores principales: Larabee, Jason L., Bland, Sarah J., Hunt, Jonathan J., Ballard, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433098/
https://www.ncbi.nlm.nih.gov/pubmed/28512094
http://dx.doi.org/10.1128/mBio.00503-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433098/
https://www.ncbi.nlm.nih.gov/pubmed/28512094
http://dx.doi.org/10.1128/mBio.00503-17

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