Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype

Glycoprotein B (gB) is the conserved herpesvirus fusion protein, and it is required for the entry of herpesviruses. The structure of the postfusion conformation of gB has been solved for several herpesviruses; however, the gB prefusion crystal structure and the details of how the protein refolds fro...

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Detalles Bibliográficos
Autores principales: Fan, Qing, Kopp, Sarah J., Connolly, Sarah A., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433099/
https://www.ncbi.nlm.nih.gov/pubmed/28512095
http://dx.doi.org/10.1128/mBio.00614-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433099/
https://www.ncbi.nlm.nih.gov/pubmed/28512095
http://dx.doi.org/10.1128/mBio.00614-17

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