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Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis

Glutathionylation, the formation of reversible mixed disulfides between glutathione and protein cysteine residues, is a posttranslational modification previously observed for intracellular proteins of bacteria. Here we show that Yersinia pestis LcrV, a secreted protein capping the type III secretion...

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Detalles Bibliográficos
Autores principales: Mitchell, Anthony, Tam, Christina, Elli, Derek, Charlton, Thomas, Osei-Owusu, Patrick, Fazlollahi, Farbod, Faull, Kym F., Schneewind, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433101/
https://www.ncbi.nlm.nih.gov/pubmed/28512097
http://dx.doi.org/10.1128/mBio.00646-17