Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis

BACKGROUND: Prolactin (PRL) reduces joint inflammation, pannus formation, and bone destruction in rats with polyarticular adjuvant-induced arthritis (AIA). Here, we investigate the mechanism of PRL protection against bone loss in AIA and in monoarticular AIA (MAIA). METHODS: Joint inflammation, trab...

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Detalles Bibliográficos
Autores principales: Ledesma-Colunga, Maria G., Adán, Norma, Ortiz, Georgina, Solís-Gutiérrez, Mariana, López-Barrera, Fernando, Martínez de la Escalera, Gonzalo, Clapp, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433139/
https://www.ncbi.nlm.nih.gov/pubmed/28506283
http://dx.doi.org/10.1186/s13075-017-1290-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433139/
https://www.ncbi.nlm.nih.gov/pubmed/28506283
http://dx.doi.org/10.1186/s13075-017-1290-4

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