An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets

BACKGROUND: A microRNA (miRNA) collection on the imprinted 14q32 MEG3 region has been associated with outcome in osteosarcoma. We assessed the clinical utility of this miRNA set and their association with methylation status. METHODS: We integrated coding and non-coding RNA data from three independen...

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Detalles Bibliográficos
Autores principales: Hill, Katherine E., Kelly, Andrew D., Kuijjer, Marieke L., Barry, William, Rattani, Ahmed, Garbutt, Cassandra C., Kissick, Haydn, Janeway, Katherine, Perez-Atayde, Antonio, Goldsmith, Jeffrey, Gebhardt, Mark C., Arredouani, Mohamed S., Cote, Greg, Hornicek, Francis, Choy, Edwin, Duan, Zhenfeng, Quackenbush, John, Haibe-Kains, Benjamin, Spentzos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433149/
https://www.ncbi.nlm.nih.gov/pubmed/28506242
http://dx.doi.org/10.1186/s13045-017-0465-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433149/
https://www.ncbi.nlm.nih.gov/pubmed/28506242
http://dx.doi.org/10.1186/s13045-017-0465-4

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