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Phosphazene-catalyzed desymmetrization of cyclohexadienones by dithiane addition

We report a desymmetrization of cyclohexadienones by intramolecular conjugate addition of a tethered dithiane nucleophile. Mild reaction conditions allow the formation of diversely functionalized fused bicyclic lactones. The products participate in facially selective additions from the convex surfac...

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Detalles Bibliográficos
Autores principales:	Horwitz, Matthew A, Massolo, Elisabetta, Johnson, Jeffrey S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2017
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433211/ https://www.ncbi.nlm.nih.gov/pubmed/28546832 http://dx.doi.org/10.3762/bjoc.13.75

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